List
Esther Oreoluwa Jokodola
Esther Oreoluwa Jokodola, a graduate student in chemical and biological engineering, is on the research team working to jump the gap between lab and industry-use in bioreactor fermentation.

Cyclone Engineers are collaborating with Cargill and Genomatica to scale-up fermentation processes in bioreactors in a new $2.5 million project. The award was announced this week at the White House Summit on the National Biotechnology and Biomanufacturing Initiative.

The project starts by perfecting fermentation techniques on a small laboratory scale. 

“What makes simulation and scale-up of bioreactors difficult is the fact that microorganisms, which function as small chemical factories, are heavily influenced by both the microenvironment that they are in, and also the microenvironment’s trajectory, or history,” says Dennis Vigil, professor of chemical and biological engineering “As the bioreactor size increases the heterogeneity of microenvironments increases, which makes prediction of the overall performance of the bioreactor more difficult. This is the problem we are trying to address by first understanding how microorganisms perform in a uniform homogeneous environment.” 

Rodney Fox, Hershel B. Whitney Professor, Global Initiatives, is the principal investigator, joined by Vigil. Both specialize in multiphase reactor design and analysis. CBE’s Zengyi Shao, leverages her expertise in the manipulation of microbes that drive the fermentation process, while Ted Heindel, Bergles Professor in Thermal Science and a University Professor of mechanical engineering, and Alberto Passalacqua, associate professor of mechanical engineering, bring expertise in measurement and computational fluid dynamics. 

Cargill and Genomatica will then team up to move the process to large-scale production of a new generation bio-based intermediate chemical product used by many industries. It will be produced in a new facility at Cargill’s Eddyville, Iowa, operation. 

A portion of the funding for the project is from BioMADE, a manufacturing innovation institute supported by the Department of Defense that works to advance research directed at the manufacturing of bio-based products. Iowa State is a governing member of BioMADE.

  Posts

1 2 3 5
December 12th, 2023

Mya O’Connell: Outstanding senior in chemical engineering

Hometown  Manly, Iowa  Clubs and activities  I work as a Resident Assistant and as a Peer Mentor. In the past, […]

November 16th, 2023

AIChE student chapter again records successes at annual meeting – including another Outstanding Student Chapter honor

The Outstanding Student Chapter award is presented at the meeting. Shown is AIChE student chapter representative Hailey Bates (center), ISU […]

October 27th, 2023

Brittany Hartwell named 2023 Cyclone Engineering Young Alumni Award winner

Brittany Hartwell (’11 chemical engineering) is a biomedical engineer advancing therapies and vaccines for illnesses affecting millions worldwide. As an […]

October 6th, 2023

Shao and Bardhan: Two faculty members in Chemical and Biological Engineering will see research advances with new appointments to professorships

Zengyi Shao, Hershel B. Whitney Professor, Global Initiatives Department of Chemical and Biological Engineering (CBE) associate professor Zengyi Shao (left, […]

October 3rd, 2023

Luke Roling named Jack R. and Carol A. Johnson Faculty Fellow

Luke Roling’s computational research work in the Department of Chemical and Biological Engineering (CBE) has received the support of the […]

September 7th, 2023

Honoring excellence: Cyclone Engineering faculty and staff award winners, named faculty positions and new patents

College of Engineering faculty and staff awards Early Achievement in Academic Advising: Holly Dunlay-Lott, student services specialist in materials science and […]

August 9th, 2023

Yue Wu named to collaboration role with Office of Vice President for Research

Tuteja and Wu to Serve in New Collaboration and Mentorship Roles Posted Aug 7, 2023 The Office of the Vice […]

August 9th, 2023

Iowa State researchers receive 2023 Barry Award to investigate cellular structure of pancreatic cancer tumors, improve treatment outcomes

Iowa State Researchers Receive 2023 Barry Award to Investigate Cellular Structure of Pancreatic Cancer Tumors, Improve Treatment Outcomes Caitlin Ware, […]

August 7th, 2023

Building green fertilizer system to reuse waste and cut greenhouse gas emissions

Vignesh Kumar Thoomatti Haridass, a postdoctoral research associate working with Iowa State’s Liang Dong, installs soil and stalk nitrate sensors […]

June 15th, 2023

Nigel Reuel named Stanley Chair in Interdisciplinary Engineering

Department of Chemical and Biological Engineering (CBE) associate professor Nigel Reuel has been named the Stanley Chair in Interdisciplinary Engineering. […]